Extrinsic regulation of satellite cell specification
نویسندگان
چکیده
منابع مشابه
Extrinsic Regulation of Satellite Cell Function and Muscle Regeneration Capacity during Aging
Optimal regeneration of skeletal muscle in response to injury requires the contribution of tissue resident stem cells termed satellite cells. Normally residing at the interface between the muscle fiber and overlying basal lamina it is generally understood with age the satellite cell pool exhibits decline both in number and function. Over the past decade mechanisms that contribute to these decli...
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Skeletal muscle stem cells, known as satellite cells, participate in postnatal skeletal muscle growth, regeneration, and hypertrophy. They are quiescent in the resting state, but are activated after muscle injury, and subsequently replicate and fuse into existing myofibers. The behavior of satellite cells during muscle regeneration is regulated by extrinsic factors, such as the extracellular ma...
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متن کاملREVIEW Androgen regulation of satellite cell function
Androgen treatment can enhance the size and strength of muscle. However, the mechanisms of androgen action in skeletal muscle are poorly understood. This review discusses potential mechanisms by which androgens regulate satellite cell activation and function. Studies have demonstrated that androgen administration increases satellite cell numbers in animals and humans in a dose–dependent manner....
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ژورنال
عنوان ژورنال: Stem Cell Research & Therapy
سال: 2010
ISSN: 1757-6512
DOI: 10.1186/scrt27